Lira Clinical Introduces PRO Anti-Aging Pads, a Revolutionary At-Home Treatment for Professional Skin Brightening and Exfoliating

Exclusive PRO Anti-Aging Pads exfoliate, brighten and balance with multiple acids, brightening botanicals and healing agents that reveal beautiful skin.

Dublin, CA, USA — Lira Clinical, the global leader in skin brightening, has introduced its PRO Anti-Aging Pads today, a game-changing skincare product designed to deliver professional results at-home. The PRO Anti-Aging Pads are being offered to estheticians, spas, clinics, and dermatologists to help their clients easily boost skin brightness and correction before and after in-clinic treatments.

What makes the PRO Anti-Aging Pads so revolutionary is the ability to expertly refine and brighten while renewing and healing the skin right at-home, all in one step. This product stands apart from complicated home care treatments with a lightweight pad that helps evenly dispense product while allowing clients to target trouble areas efficiently.

The groundbreaking science behind this product can be found in its specialized formula. Seven skin perfecting acids, including kojic, azelaic, salicylic, lactic and glycolic acid, are paired with Lira’s healing peptide delivery system to gently deliver active resurfacing agents into the skin. This results in a “peel-with-heal” approach to exfoliation. This innovative combination effectively aids cellular turnover lessening the appearance of fine lines and wrinkles and lightening dark spots.

The PRO Anti-Aging Pads also include an array of rich antioxidant botanicals and cutting-edge topical probiotics for optimal skin health. Natural illuminating ingredients like Halidrys Siliquosa, ginger, bearberry and mulberry energize and promote a glowing complexion for radiant results. Lira’s topical probiotic technology safeguards skin’s microbiome promoting overall skin balance and harmony.

“We recognized a need for an effective at-home treatment that provided professional exfoliation with less inflammation. It took our team two years of extensive research and development to perfect this product. The PRO Anti-Aging Pads truly embody Lira’s nature meets science philosophy and approach to corrective skincare,” said Metaxia Dalikas, CEO and cofounder of Lira Clinical.

The PRO Anti-Aging Pads are travel friendly and recommended for all skin types, including acneic and oily skin. The PRO Anti-Aging Pads are prescribed by licensed skincare professionals only and can be used 1-3 times a week depending on your skin’s tolerance. Always consult your skincare professional before using a new skincare product.

The Lira Clinical PRO Anti-Aging Pads are available in a three-ounce jars containing 40 pads – enough for two months use. Skin care professionals can learn more at http://www.liraclinical.com or access advanced aesthetic education on http://www.liraclinicalpro.com.

About Lira Clinical
Lira Clinical is the global leader in skin brightening and corrective skincare. Founded by four passionate aesthetic professionals who wanted to disrupt and design the next level of skincare with their unique expertise and think-tank philosophy. Lira Clinical believes that healthy and bright skin is the foundation for beautiful skin. Their award-winning formulas effectively combine the power of science and nature to deliver results-driven products and treatments. Continually on the cutting edge of aesthetic technology, Lira Clinical strives to deliver skincare for you to “Be Bright. Be Beautiful.”

For more information, visit http://www.liraclinical.com.

Contact:
Tom Woolf
Gumas Advertising
(415) 842-7398
twoolf@gumas.com

Dr. Sheldon Marks Authors Definitive Medical Textbook on Vasectomy Reversal

Springer Publishing Releases First Comprehensive Medical Guide Written by Leading Specialist in Male Reproductive Restoration.

Tucson, AZ, USA — Dr. Sheldon H.F. Marks, founder of the International Center for Vasectomy Reversal (ICVR), has just released a new medical textbook that promises to be the foremost medical reference for vasectomy reversal. Published by Springer, “Vasectomy Reversal: Manual of Vasovasostomy and Vasoepididymostomy” is the first medical textbook to provide a comprehensive, start-to-finish manual of vasectomy reversal for physicians interested in learning the procedure.

Dr. Marks has been performing vasectomy reversals for 35 years and his clinic, the International Center for Vasectomy Reversal (ICVR), reports up to a 99.5 percent success rate. The procedure has been successfully performed on thousands of men, no matter how much time has passed since their original vasectomy. Dr. Marks is one of the few urologists with a practice dedicated to vasectomy reversal, and in his new “Vasectomy Reversal” textbook he provides detailed instructions, including master’s techniques, tips and tricks, and protocols for handling various complications. Dr. Marks’ textbook is expected to become the definitive resource on vasectomy reversal and will be used by universities and teaching hospitals around the world.

More than 50 million men worldwide have had a vasectomy, and each year about 50,000 males in the U.S. undergo the procedure. However, life circumstances change and many men regret their decision when they lose a child, remarry, or simply realize they want to have their own children. While the vasectomy procedure itself is simple and routine, reversing the procedure requires microsurgery to reconnect the necessary tubes and there are few urologists in the country who can perform the procedure.

“A microsurgical vasectomy reversal remains the most cost-effective approach for any couple to have their own children following a vasectomy, offering unlimited attempts at natural conception. Drawing from decades of experience performing successful vasectomy reversals, I have captured what I have learned in this new medical textbook, offering step-by-step instruction, including detailed discussions of various treatment options before, during, and after the procedure. This is the same material I have been sharing with colleagues in courses and lectures, gathered in a single volume.”

Dr. Marks is a recognized expert in urological microsurgical procedures and has developed several courses on vasectomy reversal. At a recent international meeting of the American Society of Reproductive Medicine (ASRM) Dr. Marks led a roundtable on vas to epididymal bypass surgery, as well as a Special Masters symposium about advanced tips and techniques for vas-to-vas connections, vas-to-epididymal bypass and redo salvage reversal. He also is the author of the ASRM andrology certification module on vasectomy reversals and has taught a post-graduate course on vasectomy reversals for more than 12 years.

“Vasectomy Reversal: Manual of Vasovasostomy and Vasoepididymostomy” is available from Springer publishing (http://www.springer.com) in either hardcopy or electronic book form. For more information, visit http://www.springer.com/us/book/9783030004545.

About Dr. Sheldon H.F. Marks
Dr. Sheldon Marks is an internationally recognized microsurgical specialist and has been performing vasectomy reversals since 1983. He is the founder of the International Center for Vasectomy Reversal, which has treated patients from all 50 states and more than 80 countries. Dr. Marks also is the inventor of the Marks Vas Cutting Forceps as well as a regular contributor to WebMD. He also is an Associate Clinical Professor in the Division of Urology at the University of Arizona College of Medicine and Adjunct Assistant Professor in the Department of Urology, Tufts University School of Medicine, New England Medical Center in Boston. Dr. Marks practices what he believes is the lost art of caring for the unique needs of each patient as part of the “dads again” family.

For more information, visit http://www.dadsagain.com.

Media contact:
Tom Woolf
Woolf Media & Marketing
(415) 842-7398
tomw@woolfmedia.com

The Home Care Bible Now Available for Entrepreneurs Starting Their Own Senior Care Business

Founder of A Better Solution Home Care Nursing, Inc., Shares Tips and Techniques for Operating a Successful Home Health Care Operation.

San Diego, CA, USA — The Home Care Bible is now available for entrepreneurs seeking to launch a successful business offering home care services to seniors. Written by Lia Smith-Pratt (http://liasmith.net), CEO of A Better Solution (ABS) Home Care & Nursing, The Home Care Bible shares her experience and business tips from more than 30 years in health care and 18 years at ABS providing home and nursing services to seniors.

According to the Family Caregiver Alliance there are more than 8.4 million American seniors that receive long-term care services annually, and 27 million seniors will need some form of care by 2050. As a result, the home care is currently a $93.4 billion industry growing at an annual rate of 3.4 percent. Since more than 90 percent of aging Americans are opting for home health care, so the need for independent home care providers continues to grow at a dramatic pace. The Home Care Bible was written specifically for nurses, therapists, and non-medical professionals seeking to become their own boss and establish their own senior care practice.

“After working with so many home care providers over the years I have seen all the mistakes as well as a variety of successes,” said Smith-Pratt. “To be a winner in home care you need to adopt the right mindset and know where to look for potential pitfalls that could sink your business. Although I originally wrote The Home Care Bible to help ABS franchise partners, the book contains valuable lessons for anyone considering entering the home senior care field.”

In The Home Care Bible, Smith-Pratt shares her tips and techniques to home senior care business owners in how to avoid costly mistakes and build a successful business. It also illustrates how to build a care business with a culture of integrity and dedication to the Spirit of Service.

The Home Care Bible is available in paperback from Amazon or online at http://liasmith.net.

About Lia Smith-Pratt
Lia Smith-Pratt is the author of several books, including “Spiritual Lessons for my Daughters” and “Smart Steps to Big Dreams.” She also is founder and CEO of A Better Solution (ABS) Home Care & Nursing, which has been providing quality home care to seniors for 18 years through its care and placement services and ABS franchisees. When she is not working as CEO of ABS Home Care Nursing, she shares her business insight and experience as a business coach and inspirational speaker.

Smith-Pratt makes her home in San Diego.

Media Contact:
Lia Smith-Pratt
619-585-9011
liasmith@cox.net

Significant Reductions in Costly Pulmonary Complications with Use of Drug-Free Device

Plattsburgh, NY, USA — Post-operative pulmonary complications (PPCs) are a major burden to the healthcare system. A new real-world study published in Pulmonary Therapy, indicates significant reductions in costs when using the AEROBIKA® oscillating positive expiratory pressure (OPEP) device in the postoperative care setting.(1) The retrospective database analysis including 288 patients undergoing cardiac, thoracic or upper abdominal surgery suggests that use of the AEROBIKA® OPEP device in addition to standard of care (incentive spirometry, IS) was associated with fewer re-hospitalizations, shorter hospital stays and lower costs compared with patients using standard of care alone.

At 30 days post-discharge, significantly fewer patients in the AEROBIKA® OPEP device cohort were re-hospitalized (13.9 vs. 22.9%; p=0.042), and mean length of hospital stay was significantly shorter (1.25±4.04 days vs. 2.60±8.24 days; p=0.047) compared with the IS cohort. Costs due to hospitalizations were 80% lower in the AEROBIKA® OPEP device group (p=0.001).

The burden of PPCs, especially in patients undergoing abdominal, thoracic or cardiac surgery, is substantial:

• death rate is higher compared with patients who don’t have PPCs (at 30 days mortality is up to 10 times higher, and at 90 days up to 20 times higher)

• resource use and costs are significantly increased (mainly due to longer length of hospital stay); a US database study of over 700,000 patients predicted that PPCs could lead to an additional 9,500 deaths, 92,000 extra ICU admissions and overall added costs to the US of US$3.42 billion.(2)

The causes of PPCs may be related to, among other things, shallow breathing and reduced airway clearance, therefore physical therapy techniques that increase lung volume and clearance have been recommended to reduce the risk and severity of PPCs. One such technique is incentive spirometry (IS), which encourages the patient to take long, slow breaths by inhaling through a device to raise a ball or piston.(3) The use of IS is common in clinical practice although there appears to be little evidence to support its value.(3,4) Another commonly used intervention to prevent and treat PPCs is positive expiratory pressure (PEP) therapy, which involves breathing against expiratory resistance.

The AEROBIKA® OPEP device is an easy-to-use, drug-free oscillating positive expiratory pressure (OPEP) device; when the patient exhales through the device, intermittent resistance creates a unique pressure-oscillation dynamic, which expands the airways and helps expel mucus to the upper airways where it can be coughed out. Clinical trial and real-world data have shown that the AEROBIKA® OPEP device increases lung volume, reduces hyperinflation and improves airway clearance in patients with COPD(5) or bronchiectasis,(6) as well as reducing exacerbations in patients with COPD.(7) These observations suggested a potential value for the device in preventing PPCs, leading the authors to conduct this retrospective real-world database study.

Co-author Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development, commented that “based on the study findings, and taking into consideration both the low cost and low risk safety profile of the AEROBIKA® OPEP device, I would suggest that it could be beneficial to include as standard of care in all such post-operative patients”, noting that future studies are warranted to further define the benefits. He went on to add “The fact that patients in the AEROBIKA® OPEP device group in our study incurred lower healthcare costs in the 30-day period following discharge (mainly as a result of fewer complications requiring readmission) is particularly relevant as providers and insurers look to reduce early rehospitalization.”

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AEROECLIPSE® II BAN, AEROCHAMBER PLUS® aVHC and the AEROBIKA® OPEP device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

About the AEROBIKA® Device
The AEROBIKA® OPEP device (http://www.monaghanmed.com/aerobika) is a hand-held, robust, easy-to-use, drug-free oscillating positive expiratory pressure (OPEP) device designed to help expel mucus from the lungs, expand airways and enhance drug deposition. When the patient exhales through the device, intermittent resistance creates a unique pressure-oscillation dynamic, which expands the airways, helps expel the mucus to the upper airways where it can be coughed out. The AEROBIKA® OPEP device is designed to function independent of angle of use or flow rate, and allows for a direct aerosol pathway for patients using a nebulizer for medication delivery. The AEROBIKA® OPEP device has been shown to significantly improve forced vital capacity (FVC), 6-min walk distance (6MWD), and St. George’s Respiratory Questionnaire (SGRQ) score in COPD patients.(8) The AEROBIKA® OPEP device is available in the US via Monaghan Medical Corporation, and in Canada, Mexico, and select European countries including the UK and Germany through Trudell Medical International (http://www.trudellmed.com). (http://www.monaghanmed.com/Aerobika-OPEP)

About the study
This retrospective database study utilized patient data stored in IQVIA’s proprietary Hospital Charge Detail Master (CDM) database. The CDM database manages daily transactional patient charges from over 650 hospitals from 46 states in the USA, covering 7 million annual inpatient stays and 60 million annual outpatient visits. A total of 887 cardiac, thoracic or upper abdominal surgery patients hospitalized between 1 September 2013 and 30 April 2017 were identified to have used the AEROBIKA® OPEP device (in addition to standard of care, incentive spirometry), of whom 144 matched the selection criteria. The comparison cohort was 144 propensity-score matched subjects who had used IS alone.

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

Words or phrases accompanied by ® are trademarks and registered trademarks of Monaghan Medical Corporation or an affiliate of Monaghan Medical Corporation. © 2018 Monaghan Medical Corporation.

1. Burudpakdee C, Near AM, Huang H, Coppolo D, Kushnarev V, Suggett J. A Real-World Evidence Study Assessing the Impact of Adding the Aerobika® Oscillating Positive Expiratory Pressure Device to Standard of Care Upon Healthcare Resource Utilization and Costs in Post-Operative Patients. Pulmonary Therapy. 2018.
2. Linde-Zwirble W, Bloom J, Mecca R, Hansell D. Postoperative pulmonary complications in adult elective surgery patients in the US: severity, outcomes and resources use. Critical Care. 2010;14 (Suppl 1):P210.
3. Restrepo RD, Wettstein R, Wittnebel L, Tracy M. Incentive spirometry: 2011. Respiratory care. 2011;56(10):1600-1604.
4. Carvalho CR, Paisani DM, Lunardi AC. Incentive spirometry in major surgeries: a systematic review. Revista brasileira de fisioterapia (Sao Carlos (Sao Paulo, Brazil)). 2011;15(5):343-350.
5. Svenningsen S, Paulin GA, Sheikh K, et al. Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease. COPD. 2016;13(1):66-74.
6. Svenningsen S, Guo F, McCormack DG, Parraga G. Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging. Academic radiology. 2017;24(1):4-12.
7. Burudpakdee C, Seetasith A, Dunne P, et al. A real-world study of 30-day exacerbation outcomes in chronic obstructive pulmonary disease (COPD) patient managed with Aerobika® OPEP. Pulmonary Therapeutics. 2017.
8. Khoudigian-Sinani S, Kowal S, Suggett JA, Coppolo DP. Cost-effectiveness of the Aerobika® oscillating positive expiratory pressure device in the management of COPD exacerbations. International journal of chronic obstructive pulmonary disease. 2017;12:3065-3073.

New Published Evidence Reinforces the Importance of Device Choice in Asthma Control

Two new publications build on previous evidence that not all devices are equally effective in delivering asthma control.

Plattsburgh, NY, USA — A recent article in Pulmonary Pharmacology and Physiology[1] provides in vitro evidence that the AEROCHAMBER PLUS® FLOW-VU® valved holding chamber (or spacer) delivers aerosolized drug more effectively than other chambers, a view further supported in a new literature review published in Therapeutic Advances in Respiratory Disease.[2]

The use of spacers with Metered Dose Inhalers (MDIs) has become firmly established in the management of asthma and COPD, with guidelines such as the Global Initiative for Asthma (GINA)[3] recommending their use to reduce oropharyngeal deposition of drug and counter the common problem of poor inhaler technique. What is not established, however, is whether there are any meaningful differences between the devices. While GINA guidelines do indicate that not all are the same – a view echoed by the European Medicines Agency (EMA) recommendations,[4] which state that data for MDIs should be generated with a ‘specific named spacer’ – this view is not expressed in all guidelines. Two recent publications set out to address the impact of spacer design on drug delivery performance and look at potential implications for clinical use.

Four similarly sized chambers were compared ‘out of the box’ in terms of statistical equivalence with the gold standard AEROCHAMBER PLUS® chamber with respect to retention of drug particles within the device and the aerodynamic particle size distribution of the drug particles delivered. Only the AEROCHAMBER PLUS® FLOW-VU® chamber (Monaghan Medical Corporation) demonstrated an equivalent profile of dose retention and delivery versus the reference chamber. The Compact Space Chamber Plus† (Medical Developments), the OptiChamber Diamond† (Philips Respironics, Inc), and InspiraChamber† (Lupin Pharmaceuticals, Inc) devices all retained approximately twice as much drug, delivering around half the dose and showing non-equivalent performance compared with the AEROCHAMBER PLUS® FLOW-VU® chamber and reference chamber (pretreated AEROCHAMBER PLUS® chamber).

Lead author, Dr Sanjeeva Dissanayake, has recently published a literature review in Therapeutic Advances in Respiratory Disease, which provides further support for these findings. In considering the important attributes of such delivery devices, the review notes a shift in emphasis from chamber size and shape to other aspects, such as consistency of drug delivery, static charge reduction, valve performance, and factors optimizing facemask effectiveness (such as flexibility and seal). Despite the general lack of published clinical studies that confirm the therapeutic benefits of such differences, the AEROCHAMBER® ‘family’ of chambers has amassed an impressive body of clinical evidence. Most recently, a real-world database study[5] has demonstrated improved clinical benefits and reduced resource utilization use with the AEROCHAMBER PLUS® FLOW-VU® chamber versus other chambers in patients with asthma. A study specifically looking at the FLOW-VU® inhalation indicator has also shown benefits for carer confidence in dose delivery, and improved care-giver preference and quality of life.[6]

Dr Dissanayake commented, ‘The in vitro equivalence study results and the literature review findings provide strong support for the EMA guideline recommendations that data for MDIs should be generated with specific spacer devices, and further reinforce the view that superficially similar chambers should not automatically be considered to be interchangeable – even if superficially similar’.

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AEROECLIPSE® II BAN, AEROCHAMBER PLUS® aVHC and the AEROBIKA® device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

About AEROCHAMBER® brand valved holding chambers (VHC), including the AEROCHAMBER PLUS® FLOW-VU® AVHC
Developed in 1983 to address the needs of asthma and COPD patients having difficulty in taking their MDI medications correctly, the AEROCHAMBER® brand of chamber has innovated continuously to improve patient ease of use and quality of life as well as clinical outcomes and healthcare system savings.

• The AEROCHAMBER® brand is the global leader of chambers, with safety and efficacy validated in numerous third party clinical evaluations amongst various patient populations; it is the chamber most recommended by leading MDI pharmaceutical companies.[7]

• AEROCHAMBER PLUS® FLOW-VU® chamber is designed to deliver the intended prescribed dose via the MDI, similar to using an MDI with perfect technique. An additional feature is the incorporation of the FLOW-VU® inspiratory indicator for the care-giver to observe effective inhalation. The FLOW-VU® indicator provides real time feedback confirming an effective inhalation and ensures that there are no leakages of ambient air into the space between facemask and face, that could prevent medication delivery altogether. (http://www.monaghanmed.com)

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

Words or phrases accompanied by ® are trademarks and registered trademarks of Monaghan Medical Corporation or an affiliate of Monaghan Medical Corporation. † trademarks of respective company. © 2018 Monaghan Medical Corporation.

1. Dissanayake S, Nagel M, Falaschetti E, Suggett J. Are valved holding chambers (VHCs) interchangeable? An in vitro evaluation of VHC equivalence. Pulmonary Pharmacology & Therapeutics. 2018; 48:179-184 http://doi.org/10.1016/j.pupt.2017.10.005
2. Dissanayake S, Suggett J. A review of the in-vitro and in-vivo valved holding chamber (VHC) literature with a focus on the AeroChamber Plus Flow-Vu anti-static VHC. Therapeutic Advances in Respiratory Disease. 2018; 12. http://doi.org/10.1177/1753465817751346
3. Global Initiative for Asthma: Global strategy for asthma management and prevention, 2017 Available from: http://www.ginaasthma.org. 2017.
4. Dissanayake S. Application of the EU Guidelines for Pharmacokinetic Studies of Locally Acting Orally Inhaled Drug Products. Respiratory Drug Delivery 2010. Vol 12010:293-304.
5. Burudpakdee, C., Kushnarev, V., Coppolo, D. et al. Pulmonary Therapy. 2017; 3(2):283-96. http://doi.org/10.1007/s41030-017-0047-1
6. Ammari WG, Toor S, Chetcuti P, Stephenson J, Chrystyn H. Evaluation of asthma control, parents’ quality of life and preference between AeroChamber Plus and AeroChamber Plus Flow-Vu spacers in young children with asthma. The Journal of Asthma: Official journal of the Association for the Care of Asthma. 2015;52(3):301-307.
7. AeroChamber brand of holding chambers. Study Summary (September 2017). Available from: http://www.trudellmed.com/aerochamber-study-summary

Landmark Asthma Study Demonstrates Device Choice Determines Asthma Control

Monaghan Medical Corporation understands that for those with asthma, particularly children, choosing the device that best delivers their medication is an important consideration.

Plattsburgh, NY, USA — Monaghan Medical Corporation understands that for those with asthma, particularly children, choosing the device that best delivers their medication is an important consideration. Research has shown that even when using the same metered-dose inhaler (MDI), not all valved holding chambers perform equally well.[1]

A landmark real-world study involving more than 18,000 asthma patients has demonstrated superior asthma control with the AEROCHAMBER PLUS® FLOW-VU® antistatic Valved Holding Chamber (VHC) compared with other chamber devices.[2] According to the study, published in Pulmonary Therapy, use of the AEROCHAMBER PLUS® FLOW-VU® antistatic chamber resulted in delayed time to first exacerbation, fewer asthma-related emergency department visits, and lower exacerbation-related costs than control chambers.

Asthma is a common respiratory condition that affects an estimated 24.6 million people in the United States. Almost half of them, including nearly 3 million children, experience one or more asthma attack in a year.[3]

As opposed to systemic medications, inhalation is the recommended way to administer asthma medications because it directly targets the drug to the lungs while reducing potential side effects. Inhaled corticosteroids and bronchodilators administered by MDIs are the mainstay of long-term asthma treatment, the goals of which are to improve symptoms and prevent the occurrence of exacerbations.[4]

Poor inhaler operation by users is common, resulting in less of the delivered drug reaching the lungs. Instead, much of it is deposited on the back of the throat (oropharyngeal deposition) and then swallowed.[5] Research shows that between 28% and 68% of patients do not use inhalers well enough to benefit from prescribed medication.[6] In addition, 25% of costs associated with inhalers is wasted due to poor inhaler technique.[6]

Chambers are designed to reduce oropharyngeal deposition by changing the particle size distribution of the inhaled aerosol, and by holding the aerosol in the chamber until the patient is ready to inhale, which reduces the need for good coordination between inhalation and inhaler actuation.[7] Effectiveness of these devices can be adversely affected by the design, including the chamber electrostatic charge, a commonly reported cause of inconsistent medication delivery.[8]

Global respiratory guidelines recommend the use of chambers to improve MDI drug delivery.[4] American Thoracic Society and American Association for Respiratory Care Clinical Practice Guidelines state that the addition of a chamber is recommended and helpful.[9,10] Research also indicates that patients who use a chamber with an MDI have better asthma control than those using an MDI alone.[11]

In this new study, Dr. Chakkarin Burudpakdee (QuintilesIMS, Fairfax, VA, USA) and colleagues compared the effects of the antistatic AEROCHAMBER PLUS® FLOW-VU® aVHC and control chambers on treatment outcomes, resource use, and healthcare costs in a real-world asthma population.[2] More than 18,000 patients were included from an adjudicated claims database containing medical and pharmacy claims for more than 150 million U.S. health plan members.[2]

The analysis showed that among patients with at least 30 days of follow-up, those using the AEROCHAMBER PLUS® FLOW-VU® antistatic VHC experienced a delay in the time to first exacerbation and had fewer asthma-related emergency room visits. In addition, exacerbation-related costs were lower when compared to those using the control (non-antistatic) chambers.[2] A trend toward lower exacerbation rates per patient for the AEROCHAMBER PLUS® FLOW-VU® aVHC was sustained throughout the 12 months of the study.[2]

“This landmark study using a large volume of real-world evidence generated from thousands of patients shows the value of optimizing drug delivery in asthma management and further supports that chambers are not interchangeable,” said co-author Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development. “The reduction in exacerbation incidents among users of the AEROCHAMBER PLUS® FLOW-VU® chamber is particularly notable because experiencing an exacerbation is a risk factor for future exacerbation events-and minimizing exacerbation risk is a key goal of treatment.”

“The European Medicines Agency recommended in 2009 that development of a MDI should include the testing of at least one specific, named chamber, and that any substitution must be supported by appropriate in vitro or clinical data demonstrating equivalence,” he said. “We presented laboratory data at the recent Respiratory Drug Delivery Europe meeting[2] that confirmed that not all chambers perform equally well with the same MDI, which underlines the importance of recognizing the impact and potential risks of substituting one device for another.”

About Monaghan Medical Corporation
Monaghan Medical Corporation (MMC) offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

About AEROCHAMBER® brand valved holding chambers, including the AEROCHAMBER PLUS® FLOW-VU® anti-static chamber
Developed in 1983 to address the needs of asthma and COPD patients having difficulty in taking their MDI medications correctly, the AEROCHAMBER® brand of chamber has innovated continuously to improve patient ease of use and quality of life as well as clinical outcomes and healthcare system savings.

• The AEROCHAMBER PLUS® valved holding chamber is the leading global chamber brand, with safety and efficacy validated in numerous third-party clinical evaluations among various patient populations. It is the chamber most recommended by leading MDI pharmaceutical companies.
• AEROCHAMBER PLUS® FLOW-VU® chamber is an antistatic chamber designed to deliver the intended prescribed dose via the MDI, similar to using an MDI with perfect technique. An additional feature is the incorporation of the FLOW-VU® inhalation indicator for the caregiver to observe effective inhalation. A recent study showed that caregiver quality of life improved almost four-fold when using the AEROCHAMBER PLUS® chamber with FLOW-VU® indicator versus the same chamber without the indicator.[12] The FLOW-VU® indicator provides real-time feedback confirming an effective inhalation and that there are no leakages of ambient air into the space between facemask and face, which could prevent medication delivery altogether. (http://www.monaghanmed.com/AeroChamber-Plus-Flow-Vu-aVHC2)

About the study
Data for more than 18,000 patients with an asthma diagnosis were analysed from the QuintilesIMS Real-World Data Adjudicated Claims Database (PharMetrics Plus) between 1/2010 and 8/2015-9,325 using the AEROCHAMBER PLUS® FLOW-VU® antistatic VHC and a propensity-matched comparison cohort of 9,325 non-antistatic VHCs. Exacerbation incident rates (IR), time to first exacerbation using Kaplan-Meier survival analysis, occurrence of exacerbations, and healthcare resource use and costs were compared.

• Exacerbation IR/100 person-days (95% CI) was significantly higher in the control device cohort than the antistatic chamber cohort (0.161 [0.150-0.172] vs.0.137 [0.128-0.147]); more patients in the antistatic chamber cohort remained exacerbation free.
• 4,293 patients in each cohort were followed up for (greater than or equal to)12 months, during which there was a trend for patients in the antistatic VHC group to be less likely (10-12%) to experience an exacerbation. Fewer patients using the antistatic VHC had an ED visit compared with those in the control group (10.8% vs. 12.4%).
• Exacerbation-related costs for the antistatic VHC cohort were 23%, 25%, 20%, and 12% lower than the control device cohort at 1, 6, 9, and 12 months, respectively.

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

Words or phrases accompanied by ® are trademarks and registered trademarks of Monaghan Medical Corporation or an affiliate of Monaghan Medical Corporation. © 2017 Monaghan Medical Corporation.

References

1 Nagel MW, Suggett JA. Equivalence evaluation of valved holding chambers (VHCs) with albuterol pressurized metered dose inhaler (pMDI). Respiratory Drug Delivery Europe; April 25-28, 2017, 2017; Nice, France.

2 Burudpakdee C, Kushnarev V, Coppolo D, Suggett J. A retrospective study of the effectiveness of the AeroChamber Plus® Flow-Vu® Antistatic Valved Holding Chamber for asthma control. Pulmonary Therapy. 2017. http://doi.org/10.1007/s41030-017-0047-1. Accessed July 14.

3 Asthma Facts. United States Environmental Protection Agency. EPA-402-F-04-019. May 2017.

4 Global Initiative for Asthma: Global strategy for asthma management and prevention, 2017. Available from: http://ginasthma.org/2017-gina-report-global-strategy-for-asthma-management-and-prevention Accessed November 2017.

5 Price D, Bosnic-Anticevich S, Briggs A, et al. Inhaler competence in asthma: common errors, barriers to use and recommended solutions. Respiratory Medicine. 2013;107(1):37-46.

6 Fink JB, Rubin BK. Problems with Inhaler Use: A Call for Improved Clinician and Patient Education. Respir Care 2005;50(10):1360-74.

7 Lavorini F, Fontana GA. Targeting drugs to the airways: The role of spacer devices. Expert opinion on drug delivery. 2009;6(1):91-102.

8 Mitchell JP, Coppolo DP, Nagel MW. Electrostatics and inhaled medications: influence on delivery via pressurized metered-dose inhalers and add-on devices. Respiratory care. 2007;52(3):283-300.

9 Chung KF, et al. International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma. European Respiratory Journal 2014 ;43:343-373.

10 Ari A, et al. Aerosol Delivery Device Selection for Spontaneously Breathing Patients:2012. Respir Care 2012;57(4):613- 626.

11 Levy ML, et al. Asthma patients’ inability to use a pressurized metered-dose inhaler (pMDI) correctly correlates with poor asthma control as defined by the Global Initiative for Asthma (GINA) strategy: a retrospective analysis. Prim Care Respir J. 2013; Dec;22(4):406-11.

12 Ammari WG, et al. Evaluation of asthma control, parents’ quality of life and preference between AeroChamber Plus and AeroChamber Plus Flow-Vu spacers in young children with asthma. J Asthma 2015; 52(3):301-7.

FED Publishing Releases New Book, “My Journey, A Victory Over Cancer Through Alternative Methods” by Valarie Hendriks

My Journey, A Victory Over Cancer Through Alternative Methods, by Valarie Hendriks, is a story about one courageous woman’s journey and victory over cancer through alternative methods.

Oakland Township, MI, USA — Valarie Hendriks’ My Journey, A Victory Over Cancer Through Alternative Methods is a book that will make you laugh, make you cry, inspire you and motivate you. However, most of all it will help you in battling one of the most dreaded diseases plaguing mankind, cancer.

Valarie Hendriks grew up in the Midwest part of the United States. After college she got a job in the Optical field and is currently working as a Manager and ABO Certified Optician. Along the way she got married to her spouse of twenty five years. Her hobbies are tennis, horseback riding and Ball Room Dancing. She competed in Ball Room Dancing and won several competitions over her career. Then one day she was diagnosed with cancer. At this point in her life she thought her entire world was falling apart. However, she was determined to defeat this dreaded disease.

Her book My Journey, A Victory Over Cancer Through Alternative Methods is a book that Valarie wrote that outlines how she beat cancer. In her book she provides all of the information that she learned through two years of research so that she could help other people in their battle against cancer without going through the trauma of traditional cancer treatments. Her book is uplifting, inspiring, and motivational. It will make you laugh and it will make you cry but most of all it could help you to defeat one of the most dreaded diseases in the world, the disease that we call cancer.

Genre – Cancer, Cure, Alternative Methods, Alternative Medicine, Cancer Cure, Inspiration, Treatment, Motivational

The ebook version of My Journey, A Victory Over Cancer Through Alternative Methods ISBN 9781506903477, published by First Edition Design Publishing (http://www.firsteditiondesignpublishing.com), is available on-line wherever ebooks are sold. The 194 page print book version, ISBN 9781506903460, and ISBN 9781506903453 hardback, are published by First Edition Design Publishing and distributed worldwide to online booksellers.

Media Contact:
Valarie Hendriks
+1(941)921-2607
monty-nbf@att.net

Significant Cost Reduction in COPD Care With Simple, Drug-free Device

Aerobika® OPEP device proves to be a cost-effective treatment option in the management of post-exacerbation COPD patients.

Plattsburgh, NY, USA — The Aerobika® Oscillating Positive Expiratory Pressure (OPEP) device (Monaghan Medical Corporation) is a cost-effective treatment option in the management of COPD exacerbations, according to a study published October 20th in the International Journal of COPD.[1] This study, which used data from the published literature and national fee schedules to model the cost-effectiveness of the Aerobika® OPEP device, shows that it provides both clinical benefit and direct medical cost savings in a post-exacerbation care COPD population.

COPD is a major (and growing) source of morbidity, mortality and healthcare utilization, with hospitalization for acute exacerbations being the biggest cost driver.[2] Once a patient experiences an exacerbation, the risk of further exacerbation is increased two- to four-fold[3], and many patients experience two or three exacerbations every year.[4] As many as one in five patients discharged from hospital following an exacerbation are re-admitted within 30 days.[5]

The economic burden on the healthcare system associated with COPD is significant; in the US alone, the cost of COPD in 2010 was estimated to be US $50 billion; $30 billion in direct healthcare expenditure, with the remainder accounted for by indirect costs such as productivity losses and costs to families.[6] Approximately half of the direct costs could be accounted for by hospital care for COPD exacerbations,[6] which supports the GOLD guideline treatment goals of minimizing the negative impact of exacerbations and preventing recurrences.[2] Healthcare systems in many countries acknowledge the problem, and policies are now being put in place to try to address it; the US Medicare Hospital Readmission Reduction Program penalizes hospitals for excess 30-day, all-cause readmissions after a hospitalization for an acute exacerbation of COPD.[7]

The Aerobika® OPEP device is a drug-free, handheld mechanical oscillating positive expiratory pressure (OPEP) device that has been designed to address the structural and functional challenges in the airways of patients with COPD. When the patient exhales through the device, it helps to expand the airways, loosen and expel mucus from the lungs and may also enhance drug deposition. It has been shown to improve lung function, exercise capacity and quality of life in COPD patients,[8] and a recent real-word study showed that the device reduced exacerbation rates in patients during the critical 30-day post-exacerbation period.[9] Using data from the latter study to provide real-world input, the authors of this current analysis showed cost savings ($553 per patient) and improved outcomes (equivalent to 6 fewer exacerbations per 100 patients per year) with the Aerobika® OPEP device compared with no OPEP/PEP use, and concluded that the device provides cost-effective treatment for post-exacerbation COPD patients.

The authors also used various scenarios to investigate the likelihood of the benefit continuing over a full year, and predicted further clinical and cost benefits (21 exacerbations per 100 patients per year; cost savings of $1,952 per patient). Author Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development noted, “Our model provides evidence of clinical and cost benefits of the Aerobika® OPEP device in that critical 30-day period following an exacerbation. Given the high burden of COPD – in particular, costs relating to exacerbations – in the US population, we would expect that even a small benefit would have a significant impact on the healthcare system”. He went on to say that, although further studies would be needed to validate the long-term effectiveness, these data also give a good indication that the benefits will be sustained with long-term use.

“With the increasing pressure to improve care and reduce hospital admissions, the previously-published real-world study showing exacerbation reductions in the critical 30-day post exacerbation period gave us useful insights into the benefits of integrating the Aerobika® OPEP device into standard clinical practice”, noted Dr Jason Suggett (Group Director of Global Science and Technology, TMI). “This new analysis now gives us clear evidence that such clinical benefits would be translated into cost-effectiveness in this post-exacerbation population. In addition, new data presented at CHEST 2017 demonstrating that the generation of the proprietary pressure/oscillation pattern of the Aerobika* device efficiently generates oscillations throughout a high percentage of each exhaled breath, and with consistently high pressure amplitudes. The Aerobika* device demonstrated efficient and effective performance related to therapeutic effectiveness nearly twice that of other devices tested.”[10]

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device (http://www.monaghanmed.com/aerobika) exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers.

About the Aerobika® device
The Aerobika® OPEP device (http://www.monaghanmed.com/Aerobika-OPEP) is a hand-held, robust, easy-to-use, drug-free oscillating positive expiratory pressure (OPEP) device designed to help expel mucus from the lungs, expand airways and enhance drug deposition. When the patient exhales through the device, intermittent resistance creates a unique pressure-oscillation dynamic, which expands the airways, helps expel the mucus to the upper airways where it can be coughed out. The Aerobika® OPEP device is designed to function independent of angle of use or flow rate, and allows for a direct aerosol pathway for patients using a nebulizer for medication delivery. The Aerobika® OPEP device has been shown to significantly improve forced vital capacity (FVC), 6-min walk distance (6MWD), and St. George’s Respiratory Questionnaire (SGRQ) score in COPD patients.[8] The Aerobika® OPEP device is available in the US via Monaghan Medical Corporation (http://www.monaghanmed.com), and in Canada, Mexico, and select European countries including the UK and Germany through Trudell Medical International (http://www.trudellmed.com).

About the study
A one-year Markov model was used to estimate the cost-effectiveness of the Aerobika® OPEP device in patients who had experienced an exacerbation in the previous month, or a post-exacerbation care population, with input data from the published literature and national fee schedules. Using a base-case assumption that the benefit of the Aerobika® OPEP device would last 30 days, cost-savings ($553 per patient) and improved outcomes (ie, 6 fewer exacerbations per 100 patients per year) were demonstrated when compared with no OPEP/positive expiratory pressure use. Assuming a scenario with effect beyond the conservative 30 day time frame, the Aerobika® OPEP device continued to show benefit (21 exacerbations per 100 patients per year; cost savings of $1,952 per patient). One-way sensitivity analyses were conducted for all input variables, increasing or decreasing the effect by 20%, to determine the impact of change on costs and health effects; the results supported the robustness of the base-case conclusions.

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

Words or phrases accompanied by ® are trademarks and registered trademarks of Monaghan Medical Corporation or an affiliate of Monaghan Medical Corporation. © 2017 Monaghan Medical Corporation.

1. Khoudigian S, Kowal S, Suggett J, D. C. Cost-effectiveness of the Aerobika* oscillating positive expiratory pressure device in the management of COPD exacerbations. International journal of chronic obstructive pulmonary disease. 2017;In Press.
2. Global strategy for the diagnosis, management and prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017.
3. Khakban A, Sin DD, FitzGerald JM, et al. The Projected Epidemic of Chronic Obstructive Pulmonary Disease Hospitalizations over the Next 15 Years. A Population-based Perspective. Am J Respir Crit Care Med. 2017;195(3):287-291.
4. Puhan MA, Chandra D, Mosenifar Z, et al. The minimal important difference of exercise tests in severe COPD. Eur Respir J. 2011;37(4):784-790.
5. Guerrero M, Crisafulli E, Liapikou A, et al. Readmission for Acute Exacerbation within 30 Days of Discharge Is Associated with a Subsequent Progressive Increase in Mortality Risk in COPD Patients: A Long-Term Observational Study. PLoS One. 2016;11(3):e0150737.
6. Guarascio AJ, Ray SM, Finch CK, Self TH. The clinical and economic burden of chronic obstructive pulmonary disease in the USA. Clinicoecon Outcomes Res. 2013;5:235-245.
7. Shah T, Press VG, Huisingh-Scheetz M, White SR. COPD Readmissions: Addressing COPD in the Era of Value-based Health Care. Chest. 2016;150(4):916-926.
8. Svenningsen S, Paulin GA, Sheikh K, et al. Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease. COPD. 2016;13(1):66-74.
9. Burudpakdee C, Seetasith A, Dunne P, et al. A real-world study of 30-day exacerbation outcomes in chronic obstructive pulmonary disease (COPD) patient managed with Aerobika OPEP. Pulmonary Therapeutics. 2017.
10. Meyer A and Suggett J. A Laboratory Assessment into the Efficiency and Effectiveness of Different Oscillating Positive Expiratory Pressure Devices by Means of Patient Simulated Expiratory Waveforms. Presented at CHEST 2017.

Monaghan Medical Corporation Receives Innovative Technology Designation from Vizient for the AEROBIKA® OPEP device

Designation recognizes products that bring improvements to the health care industry.

Plattsburgh, NY, USA — Monaghan Medical Corporation announced its AEROBIKA® Oscillating Positive Expiratory Pressure (OPEP) device has received a 2017 Innovative Technology designation from Vizient, Inc., the largest member-driven health care performance improvement company in the country. The designation was based on direct feedback from hospital experts who interacted with the AEROBIKA® OPEP device at the Vizient Innovative Technology Exchange in Denver on Sept. 14, 2017.

The AEROBIKA® OPEP device is a drug-free, handheld mechanical oscillating positive expiratory pressure (OPEP) device that has been designed to address the structural and functional challenges in the airways of patients with COPD. When the patient exhales through the device, it helps to expand the airways, loosen and expel mucus from the lungs and may also enhance drug deposition. It has been shown to improve lung function, exercise capacity and quality of life in COPD patients,1 and a real-world study showed that the device reduced exacerbation rates in patients during the critical 30-day post-exacerbation period.2 These improved outcomes (equivalent to 6 fewer exacerbations per 100 patients per year) equate to a cost savings of $553 per patient with the AEROBIKA® OPEP device compared with no OPEP/PEP use, making the device a cost-effective treatment for COPD patients.

“We are extremely pleased to have been awarded this prestigious recognition from Vizient,” said Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development. “Our device was recommended by Vizient members, which is a validation of all of the design and clinical work we have done to support our customers. We are the only OPEP device to have received this designation at this year’s Innovative Technology Exchange, and are proud it was recognized to deliver improved outcomes and enhanced safety.”

“Based on feedback from attendees at the Vizient Innovative Technology Exchange, it was determined that the AEROBIKA® OPEP device should be recognized with an Innovative Technology designation. This designation will be noted in our online member contract catalog. Congratulations to Monaghan Medical Corporation on receiving this status,” said Debbie Archer, director of procurement and Vizient Innovative Technology Program lead.

Vizient represents a diverse membership base that includes academic medical centers, pediatric facilities, community hospitals, integrated health delivery networks and non-acute health care providers and represents more than $100 billion in annual purchasing volume. Through its Innovative Technology Program, Vizient works with member-led councils and task forces to review potentially innovative products. If it is determined that a product is innovative, Vizient may award a contract outside of the competitive bid cycle.

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device exclusively, directly and through distributors, in the United States. MMC’s strength lies in its commitment to product quality, outcome based solutions for customers, and its collaboration with a state-of-the-art aerosol research laboratory. (http://www.monaghanmed.com)

1. Svenningsen S, Paulin GA, Sheikh K, et al. Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease. COPD. 2016;13(1):66-74.
2. Burudpakdee C, Seetasith A, Dunne P, et al. A real-world study of 30-day exacerbation outcomes in chronic obstructive pulmonary disease (COPD) patient managed with Aerobika OPEP. Pulmonary Therapeutics. 2017.

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

Stanford University Trial Demonstrates Accuracy of Accuro Automated Ultrasound

Anesthesia & Analgesia Publishes Results of RIVANNA’s Image-Guided Technology’s Epidural Success.

Charlottesville, VA, USA — A clinical trial conducted at Stanford University Medical Center published this week in Anesthesia & Analgesia* proved the accuracy of the Accuro® image-guided spinal navigation system in calculating the optimal site and needle depth for epidural anesthesia administration. The research is the latest in a series of studies supporting the efficacy of RIVANNA‘s handheld ultrasound system with proprietary pattern recognition software, which identifies spinal landmarks and provides automated epidural placement guidance. The innovative Accuro platform also has application in a range of additional medical procedures that benefit from visualization of targeted anatomical areas.

In the trial, RIVANNA® Accuro identified the appropriate epidural injection sites along the lower spine and calculated the depth to the epidural space, a narrow hollow area in the spine. Actual epidural depth was confirmed by measuring needle penetration during successful epidural delivery by anesthesia providers. Accuro predicted this depth within an average of .61 cm.

In addition, Accuro identified the appropriate spinal interspace for needle insertion in 94% of patients and enabled 87% success in first-attempt epidural administration. The research was conducted under the direction of Brendan Carvalho, MD, at Stanford Medical Center and led by Katherine Seligman, MD, currently faculty at the University of New Mexico.

“The ability to visualize spinal anatomy in detail during epidural needle placement has a strong impact on the procedure’s success,” says Will Mauldin, Chairman and CEO of Rivanna Medical. “Today, anesthesiologists rely on spinal palpation and their knowledge of spinal anatomy to determine the appropriate injection site and depth. Depending on the patient condition and physician skill, up to 80% of first attempt epidural needle placements fail. Obesity and atypical spinal characteristics such as scoliosis place patients significantly at failure risk.”

Repeated epidural needle insertions can negatively impact the patient with ongoing headaches, bleeding, back pain and possibly paralysis. Failed epidurals cost the medical system more than $1.5 billion annually.

Mauldin notes that ultrasound is the imaging modality of choice for epidurals because most are administered to expectant mothers who must avoid the radiation involved in other imaging procedures.

Significant research shows that ultrasound guidance of epidural and other neuraxial anesthesia significantly improves efficacy and patient safety. However, performing and interpreting ultrasound requires specialized training not typically in the anesthesia provider’s skillset.

Accuro’s SpineNav3D™ computerized ultrasound image guidance eliminates the steep ultrasound learning curve, making it simple and practical for anesthesiologists and other medical professionals not trained in the modality.

“This study published in a respected anesthesiology publication underscores the device’s precision in providing physician guidance,” says Mauldin.

In addition to innovative image guidance, RIVANNA Accuro also incorporates BoneEnhance® technology, which optimizes the device for visualization of bony spinal anatomy. Accuro delivers a five- to 10-fold increase in bone-to-tissue contrast compared to traditional ultrasound, which is generally preferred for soft tissue imaging. The pocket-sized, wireless device is simple and practical to use in a wide range of settings where traditional large, unwieldy systems can be a problem.

“Accuro is designed to eliminate the risks of multiple needle placement attempts, increasing patient satisfaction while supporting anesthesiology workflow,” notes Mauldin. “A growing number of studies underscore the device’s success in meeting these goals.”

A recent randomized trial at University of Virginia Medical Center found that for residents with prior spinal anesthesia experience, Accuro improved first-attempt needle placement by more than 100% in patients with a high body mass index. Appropriate needle placement in these patients is particularly difficult. The average number of needle redirections to achieve placement using Accuro was almost half that of the same sub-group using conventional placement methods.

* ANESTHESIA & ANALGESIA is the official journal of the International Anesthesia Research Society.

About Accuro® and Rivanna Medical, LLC
RIVANNA® Accuro is the world’s first ultrasound-guidance system designed to effortlessly enhance spinal and epidural anesthesia placement accuracy. The revolutionary platform features BoneEnhance®, which optimizes ultrasound for the visualization of bony vs. soft tissue anatomy, and SpineNav3D™, which automates measurements of the spinal midline, epidural depth and trajectory. Accuro was engineered and commercialized by RIVANNA, an innovative medical device company headquartered in Charlottesville, VA. The proprietary device is FDA 510(k)-cleared for a variety of imaging applications. For anesthesia providers, certainty can be effortless with Accuro. For more information, visit http://www.rivannamedical.com.

Copyright © by Rivanna Medical, LLC. All rights reserved. RIVANNA® and Accuro® are registered trademarks of Rivanna Medical, LLC.

Media Contact:
HealthFlash Marketing
Jeanne-Marie Phillips, 203-977-3333
jphillips@healthflashmarketing.com

Progressive Bay Area Executive Protection Teams Incorporate Medical Component to Enhance Protection of Their Principals

Bay Area Emergency & EP Professionals to Present, “Emerging Trends in Executive Protection Medical Programs” at ASIS International 2017.

Redwood City, CA, USA — Emergency University, the industry leader in corporate Emergency Response system design, emergency medical training and state-of-the-art response and collaborative technologies announced today that Dr. Odelia Braun, Medical Director of Emergency University, Eric Powell, Chief Security Officer of Bayshore Global Management, and William Killgallon, Head of Security and Crisis Management, GE Digital will lead an Impact session on, “Emerging Trends in Executive Protection Medical Programs” at the upcoming ASIS International Conference at the Kay Bailey Hutchison Convention Center in Dallas on September 26, 2017.

As Executive Protection models evolve, EP professionals are increasingly aware of the importance of integrating medical capabilities into their security protection models to reflect the needs of their principals. The panel will address the critical components to consider when designing EP Medical Programs.

After studying the challenges faced in designing these complex Executive Protection Programs, the panel of EP professionals and experienced emergency physicians developed a standardized process to evaluate the status of their current teams, and set short-term and long-term goals. They designed and implemented a coordinated program of medical protocols, targeted training programs, equipment and technology, designed to orient and prepare security teams to effectively respond to medical issues while ensuring that the solutions emphasized security first.

“Medical capability in the executive/dignitary protection arena is a critical resource. Having medical care on hand dramatically increases the probability of mission success,” Killgallon remarked. “For example, one of the primary reasons the murder rate has decreased in the last 30 years in the US is not because of less violence – there is actually more – or better law enforcement; it is because of better, faster, and closer emergency medical care – people are surviving things that used to kill them.”

A well-prepared medical program ensures the best clinical outcome for protectees experiencing medical emergencies. The presenters will emphasize due diligence, ways to minimize risk and assemble vital components into a cohesive system that predictably achieves effective medical protection.

About Emergency University: For more than 20 years, Emergency University has assisted national and global corporations and government agencies in the development of effective internal emergency response system planning and design, provided comprehensive emergency response preparedness training, as well as researched, developed and implemented Executive Protection Medical program solutions with cutting-edge technological support – ensuring their clients are 100% prepared! Emergency University’s clients enjoy an outstanding 100% response rate versus the national average of 2%. EU’s educational methodology prepares students to respond while offering its clients a one-stop solution for emergency response system design, compliance and training. Additional information on Emergency University is available at: http://www.emergencyuniversity.com.

Media Contact:
T. Farina
Emergency University
866-233-4357
tfarina@emergencyuniversity.com
http://www.emergencyuniversity.com

Finding Temporary Care for Seniors Displaced by Disaster

Many Seniors Displaced by Hurricane Harvey – How Local Senior Communities are Helping.

Dallas, TX, USA — We have all seen the horrific images of flooding and disaster along the gulf in Texas and Louisiana. This event has left thousands homeless and helpless, lacking basics as well as medical equipment, medication and help. Times like these leave the vulnerable, especially seniors, at a greater risk.

This is when neighboring communities open their doors to help those in need. From the mega-shelters, to churches, and small owner run assisted living homes, all are willing to help neighbors in need.

NewLifeStyles.com named as a Top Senior Living Website by Top5Reviewed.com, is a free, comprehensive guide to senior communities and care providers, not just in the Houston and Rockport areas, but nationwide. Where you can find senior homes offering respite, or temporary help for those displaced by the storm.

NewLifeStyles.com is a “one stop shop” where people can find and compare senior living communities & care providers across the country, from nursing homes in Texas, to assisted living and memory care in the Heartland, retirement communities in the New York and Boston, and even hospice providers in Alaska. You can find all licensed senior communities and care providers and more, including some pictures, videos, email forms, etc. The “robust blog content” contains tips for choosing a provider, moving, downsizing, caretaking and more.

We are receiving emails and notices from communities in Texas with openings, offering to take in seniors needing help. Let us help you find the help you need, rather that is temporary or long-term.

New LifeStyles is The Source for Senior Living and Care, providing free, comprehensive, quality information on senior communities and care providers nationwide. New LifeStyles offers free print guides covering many areas across the country, as well as a website and mobile site, reducing the frustration of trying to find information from multiple sources, agencies, or organizations. Whether looking for a nursing home, memory care, assisted living, independent living, home care or something else, New LifeStyles can help seniors and their loved ones make the best decisions to fit their needs.

If you would like more information about this topic, please contact at 1-800-869-9549 or jennifer@newlifestyles.com.

Media Contact:
Jennifer Campbell
New LifeStyles
800-975-9439
jennifer@newlifestyles.com
http://www.newlifestyles.com

Finally an Answer for the National Opioid Crisis

An at home program for curing opioid addiction with extremely high cure rates is revealed.

Sylva, NC, USA — Dr. Winn Henderson has just released this week his 41st book entitled: “Freedom From Addiction 3” which offers a treatment program which can be accomplished at home to cure opioid addiction. If the addicted individual meets three simple criteria there is a 100% cure rate.

Dr. Winn Henderson is a retired physician with over 20 years of clinical experience. He is the author of 41 books including The Cure of Addiction, The Four Questions, Share Your Mission, The Deposition, The Secret to Happiness, The 12 Steps, and this book, Freedom From Addiction 3. For the last 20+ years, Dr. Henderson has been counseling both in person and by telephone clients from all over the world on issues of addiction and finding one’s purpose in life. He is the host of a 17-year long radio/internet talk show: “Freedom From Addiction/Share Your Mission.” His iTunes podcast: “Freedom From Addiction” can be heard 24/7 all over the world. The doctor is immediately available for national interviews.

Media Contact:
Winn Henderson, M.D.
Freedom From Addiction
828-508-7981
winn@winnhenderson.com
http://www.freedomfromaddictionii.com

Algae Dynamics Corp Announces Research Agreement With University of Western Ontario to Investigate the Use of Cannabis Derivatives for the Development of Novel Pharmacotherapies for Mental Health

Algae Dynamics announces a development agreement with Western University to do research on cannabis oil in the context of depression, post-traumatic stress disorder & schizophrenia.

Toronto, Canada — ALGAE DYNAMICS CORP (OTCQB: ADYNF) (the “Company”), a development stage company focused on the development of unique health products and pharmaceuticals utilizing cannabis and algae oils, today announced a research and product development agreement with Western University to perform research on cannabis oil and its constituents in the context of depression, post-traumatic stress disorder, anxiety and schizophrenia. This is the second of the recently announced research agreements with Canadian universities involving cannabis oil research. This announcement brings Algae Dynamics total university research contributions to $1.6 million for both programs.

This announcement follows the Company’s previously announced new strategic initiative to explore the extraction of oils from other botanicals, most notably cannabis, and to seek product development and formulation opportunities that combine the benefits of algae and cannabis oils. This research agreement will directly support this initiative and will “focus on translational pharmaceutical research, with a specific focus on identifying how specific phytochemical compounds found in cannabis, including delta-9-tetrahydrocannbinol (THC), cannabidiol (CBD), cannabinoid-derived terpenoids and other potential phytochemical derivatives of cannabis may serve as novel pharmacological treatments for symptoms associated with depression, post-traumatic stress disorder, anxiety and schizophrenia.”

Paul Ramsay, Chairman and President of the Company said, “With this research agreement, we are building upon the previously announced strategic initiative into the use of extracts from cannabis oil, in conjunction with algae oil, to develop unique health products and formulations. In our previous press release, we outlined a three-part approach, the first being Research and Development work with Canadian universities. This is the second of such research agreements relating to the use of botanical extracts including cannabinoids that we expect to employ”.

The investigator leading the research is Dr. Steven Laviolette, a Professor and Neuroscientist in the Schulich School of Medicine & Dentistry at Western University. Dr. Laviolette is a leader in the study of cannabinoids in mental health. Dr. Laviolette’s research team has previously made numerous fundamental discoveries related to how cannabinoids impact and may serve as treatments for mental health disorders including schizophrenia, depression, post-traumatic stress disorder and anxiety. Dr. Laviolette’s primary research focus is in characterizing how specific phytochemical derivatives of cannabis may interact with specific brain pathways and molecular mechanisms whereby they may improve symptoms associated with various mental health disorders. Research from Dr. Laviolette’s team has been published in the top neuroscience and psychiatry journals in the world. His full profile may be seen on the Western University, website http://www.uwo.ca:

http://www.schulich.uwo.ca/anatomy/people/bios/faculty/laviolette_steve.html

The Company’s contribution to the four-year Sponsored Research Agreement, which commences April 1, 2017 and terminates March 30, 2021, is C$250,000 per year. The Company believes, from past experience, that it will be able to leverage the research expenditures with matching scientific grants pursuant to programs of various branches of government. The Company will be responsible for the filing of patents relating to this research and will own such patents if and when issued. The Company has agreed to make payments to the University upon filing of each patent, when each patent is issued, after first commercial sale and when gross sales reach C$1,000,000. There are no ongoing royalty payments, relating to the use of the patents. The workplan may be extended and modified to achieve best outcomes which may include 1) delegating specific research areas of research work that require additional technologies to appropriate providers; and 2) engaging research collaborators to extend the research into additional areas of benefit to the Company.

The Company’s core product development strategy has been the production of high volume specific algae species and extraction of Essential Fatty Acids (EFAs) which is the foundation of the endocannabinoid system (ECS). The ECS is a group of endogenous cannabinoid receptors located in the mammalian brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. The extracted algae Omega 3 oil with high concentrations of DHA is used as a health supplement product. In light of the potential synergies, the Company has developed its strategy which is aimed at developing new products and formulations that combine the health benefits of algae and cannabis oils.

As reported earlier, the Company is continuing to seek opportunities to partner with or take ownership in existing Access to Cannabis for Medical Purposes Regulations (ACMPR) licensed producers to allow for access to the marketplace.

About Algae Dynamics Corp
ADC is currently engaged in the development of unique health products and pharmaceuticals that utilize hemp, cannabis and algae oils. This is an extension of our plan to commercialize our proprietary BioSilo® algae cultivation system for the high volume, low cost production of pure contaminant-free algae biomass which is high in Omega-3 fatty acids. We have engaged two Canadian universities to provide research into the use of extracts from cannabis oil, which we plan to use to develop products that combine the significant health benefits of Omega-3s derived from algae oil and extracts from cannabis oil. Our research is focusing on the use of cannabis oil in the context of cancer, and the use of cannabis derivatives for the development of novel pharmacotherapies for mental health.

NOTE REGARDING FORWARD-LOOKING STATEMENTS
This news release contains “forward-looking statements” as that term is defined in Section 27A of the Securities Act and Section 21E of the Securities Exchange Act of 1934, as amended. Statements in this press release which are not purely historical are forward-looking statements and include any statements regarding beliefs, plans, expectations or intentions regarding the future. Such forward-looking statements include, among other things, use of proceeds and the development, costs and results of current or future actions and opportunities in the sector. Actual results could differ from those projected in any forward-looking statements due to numerous factors. Such factors include, among others, the inherent uncertainties associated with new projects and development stage companies, our ability to raise the additional funding we will need to continue to pursue our exploration and development program, and our ability to retain important members of our management team and attract other qualified personnel. These forward-looking statements are made as of the date of this news release, and we assume no obligation to update the forward-looking statements, or to update the reasons why actual results could differ from those projected in the forward-looking statements. Although we believe that any beliefs, plans, expectations and intentions contained in this press release are reasonable, there can be no assurance that any such beliefs, plans, expectations or intentions will prove to be accurate. Investors should consult all of the information set forth herein and should also refer to the risk factors disclosure outlined in our annual report on Form 10-K for the most recent fiscal year, our quarterly reports on Form 10-Q and other periodic reports filed from time-to-time with the Securities and Exchange Commission.

FOR MORE INFORMATION, PLEASE CONTACT:
Paul Ramsay
Phone: 289-997-6740
Email: ramsay(at)algaedynamics.com
http://www.algaedynamics.com

Monaghan’s Drug-Free Aerobika® Device Helps Reduce the Real-World Impact of Exacerbations in Chronic Obstructive Pulmonary Disease

This study provides the first real-world evidence for the benefits of using the Aerobika® device in reducing exacerbation-related emergency department visits and hospital readmissions.

monaghan-medical-corporation-logo

Syracuse, NY, USA — Monaghan Medical Corporation (MMC) (http://www.monaghanmed.com), today announced the publication of a study in Pulmonary Therapy showing that treatment with Monaghan’s Aerobika® device can significantly reduce the recurrence of exacerbations of chronic obstructive pulmonary disease (COPD) in the crucial 30-day period following hospitalization or emergency room visits.(1) The study also showed that per-patient cost of exacerbations was significantly lower in the group using the Aerobika® Oscillating Positive Expiratory Pressure (OPEP) device. This study provides the first real-world evidence for the benefits of using the Aerobika® device in reducing exacerbation-related emergency department visits and hospital readmissions.

COPD is a major (and growing) source of morbidity, mortality and healthcare utilization, with hospitalization for acute exacerbations being the biggest cost driver. Once a patient experiences an exacerbation, the risk of further exacerbation is increased two- to four-fold(2), and many patients experience two or three exacerbations every year.(3-5) As many as one in five patients discharged from hospital following an exacerbation are re-admitted within 30 days.(6)

This retrospective study analyzed hospital database records for 810 COPD Chronic Bronchitis patients who were hospitalized or visited the emergency room, and showed significantly fewer patients given the Aerobika® device experienced moderate-to-severe exacerbations or severe exacerbations compared with matched controls within the critical 30-day follow-up period. The study also showed a statistically significant savings in exacerbation-related costs in the Aerobika® device group compared with the control group for moderate-to-severe and severe exacerbations. The Aerobika® device was given in addition to the patients’ regular COPD treatments.

“This is the first study to evaluate the benefits of any OPEP in a real-world setting. It provides encouraging evidence that the Aerobika® device can help reduce recurrence of exacerbations in high-risk patients over the crucial early 30-day period,” noted Dr. Michael Bauer, Pulmonary Physician, Cooperstown, New York.

Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development at Monaghan Medical, explained how the Aerobika® device may provide these benefits: “During an exacerbation, airways are compromised by (among other factors) inflammation and mucus build-up. This can continue to disrupt ventilation mechanics and lung function after the event, and lead to prolonged respiratory impairment. The Aerobika® device, with its proprietary mechanism of action, helps stent open and clear excess mucus from the upper airways, and may also aid drug deposition, providing a potential mechanism of protection from exacerbations.”

The internationally-recognized GOLD guidelines(7) for COPD treatment stress the importance of exacerbation management, stating that a major treatment goal is to ‘minimize the negative impact of the current exacerbation and to prevent subsequent events.’ A recent analysis(2) predicts that the absolute number of COPD cases could increase by between 150% and 220% in the period from 2010 to 2030, with the burden of inpatient care (total annual inpatient days) growing by around 185%. This further underlines this need to address the burden of COPD exacerbations.

About the Aerobika® device study
A retrospective cohort study utilizing patient data from the U.S. hospital Charge Detail Master (CDM) claims database (data selection period between 1 September 2013 and 31 August 2015). This real-word study involved 810 COPD patients with a diagnosis of chronic bronchitis, 405 receiving treatment with the Aerobika® device and 405 matched controls, (propensity matched to reduce bias and mimic randomization). The data showed significantly fewer patients given the Aerobika® device experienced moderate-to-severe exacerbations (18.5% vs 25.7%, p=0.014) or severe exacerbations (13.5% vs 19.0%; p < 0.046) compared with matched controls over the 30-day follow-up period, with consequent reductions in costs.

About the Aerobika® Device
The Aerobika® device is hand-held, robust, easy-to-use, and drug-free with a proprietary mode of action. When the patient exhales through the device, intermittent resistance creates a unique pressure-oscillation dynamic, which expands the airways, helps expel the mucus to the upper airways where it can be coughed out, and may also aid in improved drug deposition. The Aerobika® device is designed to function independent of angle of use or flow rate, and allows for a direct aerosol pathway for patients using a nebulizer for medication delivery. The Aerobika® device has been shown to significantly improve forced vital capacity (FVC), 6-min walk distance (6MWD), and St. George's Respiratory Questionnaire (SGRQ) score in COPD patients.(8) The Aerobika® device is available in the U.S. from Monaghan Medical Corporation, and in Canada, Mexico, and select European countries including the UK and Germany through Trudell Medical International. (http://www.monaghanmed.com/Aerobika-OPEP)

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

References:

1. Burudpakdee C et al. Pulm Ther 2017 DOI 10.1007/s41030-017-0027-5. Pub online 6 February 2017.

2. Khakban A, et al. Am J Respir Crit Care Med 2017 Feb 1;195(3):287-291.

3. Balter MS, et al. Can Respir J 2003; 10 (Suppl B):3B-32B.

4. Perera PN, et al. COPD J Chron Obst Pulm Dis 2012;9(2):131-41.

5. Puhan MA, et al. Respir Res 2005;6 (1): 1.

6. Shah T, et al. Chest. 2016 Oct;150(4):916-926.

7. The Global Strategy for the Diagnosis, Management and Prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017. Available from: http://goldcopd.org (Last accessed 2 Feb 2017).

8. Svenningsen S, et al. COPD 2016;13(1):66-74.

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President of Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

New Study Indicates Monaghan Medical’s Drug-Free Aerobika® Device Shows Promise for Treatment of Bronchiectasis

This latest study adds to the growing base of evidence that demonstrates Monaghan’s drug-free Aerobika® device is effective for lung health maintenance.

monaghan-medical-corporation-logo

Syracuse, NY, USA — Monaghan Medical Corporation (MMC) today announced that the findings of a study published in the most recent issue of Academic Radiology shows that patients with non-cystic fibrosis (CF) bronchiectasis responded favorably to airway maintenance therapy using the Aerobika® device. This latest study adds to the growing base of evidence that demonstrates Monaghan’s drug-free Aerobika® device is effective for lung health maintenance.

In this latest study, researchers noted significant improvements in ventilation function for a number of bronchiectasis patients after three weeks of using the Aerobika® device. There were no adverse events related to the use of the device reported during the study.(1)

Bronchiectasis is a condition in which the structure and function of the airways become permanently damaged, usually as the result of infection or other condition. Patients suffering from chronic bronchiectasis typically have trouble clearing mucus from airways and suffer from a repeating pattern of airway damage, mucus buildup, and recurrent infections. The result is typically a vicious cycle of decline, resulting in reduced air exchange in the smaller airways.

There are three primary goals in the successful treatment of bronchiectasis:

1. Treat any underlying conditions and lung infections
2. Remove mucus from the lungs, and
3. Prevent complications

“This most recent study just adds to the mounting clinical evidence that our Aerobika® device is effective for patients with bronchiectasis, COPD, and related respiratory disease,” said Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development at Monaghan Medical. “We are always pleased to see real-world findings that demonstrate the efficacy of our Aerobika® device in clearing mucus to improve lung function in patients with chronic bronchial ailments as well as high-risk COPD patients.”

Overlap between bronchiectasis and COPD

Researchers have observed overlap between bronchiectasis and other chronic airway diseases such as chronic obstructive pulmonary disease (COPD). Studies show that these types of patients tend to have higher rates of exacerbation and worse outcomes.(1) The overlap between bronchiectasis and COPD was highlighted in a recent study presented at the 2016 CHEST annual meeting in October. Investigators found that 92.7 percent of COPD patients who had experienced more than one exacerbation in the previous 12 months also had bronchiectasis.(2)

The results of the study published in Academic Radiology showing effectiveness in treating bronchiectasis patients using the Aerobika® device are in line with another 2016 real-world study presented at the European Respiratory Society (ERS) International Congress. Investigators found the Aerobika® device demonstrated a clinically significant reduction in exacerbations in as little as 30 days of treatment when used as an add-on to usual COPD medications.(3)

About the bronchiectasis Aerobika® device study
Fifteen participants with non-CF bronchiectasis and 15 age-matched healthy volunteers underwent spirometry, plethysmography, computed tomography (CT), and hyperpolarized (3) He magnetic resonance imaging (MRI). Bronchiectasis patients also completed a Six-Minute Walk Test, the St. George’s Respiratory questionnaire, and Patient Evaluation Questionnaire (PEQ), and returned for a follow-up visit after three weeks of daily oscillatory positive expiratory pressure (Aerobika® device) use. Supplementary data related to this study can be found at dx.doi.org/10.1016/j.acra.2016.08.021.

About the bronchiectasis and COPD overlap study
A retrospective study of the medical records of 961 stable COPD outpatients who were followed regularly during the period 2011-2015 at least twice/year. Complete medical records were found in 855 patients who were eligible for the analysis. Results were presented at the 2016 CHEST annual meeting.

The complete study can be found at http://journal.publications.chestnet.org/article.aspx?articleid=2568609

About the Aerobika® device real-world COPD study
A retrospective cohort study of the CDM hospital claims database was conducted between September 2013 and August 2015. The final study sample comprised of 810 patients; 405 received an Aerobika® device and 405 were propensity score matched. The study inclusion criteria were: =1 record pre-index, =1 record post-index, newly initiated on the Aerobika® device, =1 diagnosis of CB on/before index, =18 years old, no evidence of other PEP/OPEP anytime, with complete records. See more at: http://erj.ersjournals.com/content/48/suppl_60/PA3780

About the Aerobika® device
The Aerobika® device is hand-held, easy-to-use and drug-free. When the patient exhales through the device, intermittent resistance creates positive pressure and oscillations simultaneously, which expands the airways, helps expel the mucus to the upper airways where it can be coughed out, and may also aid in improved drug deposition. The Aerobika® device is available in Canada, Mexico, and select European countries including the UK and Germany through Trudell Medical International and in the US via Monaghan Medical Corporation. (http://www.monaghanmed.com/Aerobika-OPEP)

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President of Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

References:
[1] Svenningsen S et al. Noncystic Fibrosis Bronchiectasis: Regional Abnormalities and Response to Airway Clearance Therapy Using Pulmonary Functional Magnetic Resonance Imaging. Acad Radiol. January 2017; 24:1,4-12.
[2] Kosmas E, et al. Bronchiectasis in Patients With COPD: An Irrelevant Imaging Finding or a Clinically Important Phenotype? Chest. 2016;150(4_S):894A.
[3] Suggett J. A Retrospective Cohort Study Demonstrating the Impact of an OPEP Device on Exacerbations in COPD Patients with Chronic Bronchitis. Presented at ERS 2016. Eur Respir J. 2016;48:PA3780.

No.1 Type 2 Diabetes Book FREE on Kindle November 29 – December 3

New Book Shares Secrets to a Normal Life For Type 2 Diabetics by Following Simple Steps.

type-2-diabetes-the-owner-s-manual

Modesto, CA, USA — “Type 2 Diabetes is totally manageable, especially if you can catch it early,” stresses Daryl Wein, author of Type 2 Diabetes: The Owner’s Manual.

The ebook is free on Kindle Nov. 29 thru Dec. 3rd.

“The single most effective thing the patient needs to do is eliminate or at least minimize their carb intake. I have Type 2 Diabetes myself and went nine years living a very healthy life without medicine because I followed a correct diet which did not allow for sugar or carbs.”

A clinical laboratory scientist for more than 20 years and a Physician Assistant for 17 years, Wein started extensive research on Type 2 Diabetes when he himself was diagnosed with the disease.

After directing successful treatment for many hundreds of patients by informing them of the correct diet for them, Wein decided to share those secrets with patients and physicians alike in his new book Type 2 Diabetes: The Owner’s Manual (ISBN 978-1522858270, CreateSpace 2016, 159 pages, available on Amazon $11.99 paperback and Audio Book (regularly $6.99 on Kindle but FREE thru Dec. 3rd).

“To my knowledge my book is the only simple owner’s manual for Type 2 Diabetes,” says Wein. “It teaches readers to utilize first the most effective option available to manage their disease and then to fine-tune sugar control with medication when and if needed. The Owner’s Manual is very simple to read and understand.”

type-2-diabetes-the-owner-s-manual-daryl-wein

While working for Central California Bariatric Surgery Daryl Wein made it his objective to help patients reach their needed weight goal via diet instead of surgery and experienced multiple successes including one patient who lost 149 pounds over 22 months simply by avoiding carbohydrates completely.

Wein stresses that if all people with sugar abnormalities (who are not dependent on insulin) followed the simple advice in Type 2 Diabetes: The Owner’s Manual the impact on their overall health would be immense and the savings for healthcare in the U.S. alone would be in the many billions of dollars.

James A. Surrell, M.D. and author of SOS (Stop Only Sugar) Diet, says: “We have an epidemic of Type 2 diabetes in the USA today, primarily as a result of our dietary habits. Follow the excellent guidelines contained in Type 2 Diabetes: The Owner’s Manual and you will significantly improve your overall health.”

A physician in a review on Amazon using the pen name “Schmutz” writes: “The Owner’s Manual is well written, easy to understand in laymen’s terms and very useful. If diabetics followed Daryl’s recommendations, my job would be much easier and their lives healthier and longer.”

A few of the eye-opening pieces of advice given by Wein in his highly-respected book include:

• There is no need to consume any sugar or starches at all
• Natural fruit and fruit juices are not good for diabetics
• Avoid all forms of alcohol when trying to lose weight
• The only fats known to be harmful are trans-fats which are mainly found in shortening and margarine
• Eating fat does not make you fat and eating fat has never been directly associated with heart disease
• Brown sugar has never been healthier than white sugar, only less pure
• There are almost no carbs in any of the artificial sweeteners so they do not contribute to the elevation of blood sugar.
• Monitoring your sugar 2-3 times a day with a finger stick test is costly and a complete waste of time.

A former flight instructor, Wein also enjoys water skiing, swimming, building houseboats, and playing the bass which he did while earning his living as a musician, playing in clubs for three years. He owns a small plane but his latest flight interest is flying industrial drones legally. Daryl and wife Jann have an adult daughter, an adult son, and three grandchildren.

November is National Diabetes Month to help put a spotlight on the disease so individuals, health care professionals, organizations, and communities across the country can bring attention to diabetes and its impact on millions of Americans. Visit: http://www.diabetes.org.

About Daryl Wein
A native of Niles, Michigan, Wein earned a degree as a Medical Technologist/Clinical Laboratory Scientist from USC Medical Center in 1978 and earned a degree as a Family Practice Physician Assistant from UC Davis School of Medicine in 1999. Since 1999, while working as a PA with Dr. David Olson and Dr. Elaine Madayag in internal medicine, Wein also worked as a PA at Stanislaus County Urgent Care, Oak Valley Hospital ER, Central California Bariatric Surgery, as a contractor for California Correctional Health Care System, and for rural health clinics run by Oak Valley Clinics. He also has done some software development, and is credentialed in California to teach community college classes.

Media Contact: For a review copy of Type 2 Diabetes: The Owner’s Manual or to arrange an interview with Daryl Wein contact Scott Lorenz of Westwind Communications Book Marketing by phone at 734-667-2090 or http://www.book-marketing-expert.com.

University of California San Diego Enters Into Licensing and Intellectual Property Agreement with Global Cancer Technology, Inc.

License agreement reached with UCSD office of innovation and commercialization for patent and intellectual property for linking a drug to a nanocrystal scintillator activated radiosurgically.

global-cancer-technology-inc-logo

San Diego, CA, USA — Global Cancer Technology, Inc. announced today that the company has signed a Licensing Agreement with the University of California San Diego to bring to market a drug delivery platform that links a nanocrystal to a prodrug that can be activated using radiosurgery.

“This represents the first ever effort to utilize radiosurgery to activate a prodrug linked to a nanocrystal scintillator” said Mr. John Clark, Chairman and CEO of Global Cancer Technology, Inc. “The process allows a drug to be delivered to a tumor site and radiosurgically activated releasing 100% of the drug’s energy directly at the tumor site”. Mr. Clark went on to say that “aside from its use in fighting cancer, this delivery platform when activated by exceedingly low, regionally focused doses of radiation can provide tremendous benefits in infectious disease drug treatments in terms of selectivity, dosing, and tolerability”.

Drs. Milan Makale, Wolf Wrasidlo and Santosh Kesari, principal inventors of the patented process jointly commented, “The University is very pleased to be moving this transformative technology forward and working with Global Cancer Technology, Inc. in the commercialization process”. They added “UC San Diego is excited about the prospect of advancing cancer and infectious disease drug delivery improvements for patients and the medical community”.

Global Cancer Technology, Inc. provides PRODUCTS, PARTNERSHIPS and SERVICES to the worldwide medical and oncology market.

Media Contact:
Kelly O’Connor
Global Cancer Technology, Inc.
Ph: (619) 818-2411
Fax: (800) 886-3880
info@globalcancertechnology.com
http://www.globalcancertechnology.com

November is National Diabetes Awareness Month – New Lifesaving Book Helping Thousands

New Book Shares Secrets to a Normal Life For Type 2 Diabetics by Following Simple Steps.

type-2-diabetes-the-owner-s-manual

Modesto, CA, USA — Almost everyone with Type 2 Diabetes can live a normal, healthy, functional life if they receive and follow some rather simple advice they will not hear from most doctors.

The common advice given by physicians to Type 2 Diabetic patients is to reduce sugar intake, but little progress will be made until a healthy diet is followed that eliminates most carbohydrates, says Physician Assistant and author Daryl Wein.

Wein said he spends 35 to 45 minutes counseling all of his new Type 2 Diabetes patients about the importance of diet and minimizing carbs as well as sugar, while almost all physicians will only spend about five minutes with a new diabetic patient and simply advise to cut down on sugar.

“Type 2 Diabetes is totally manageable, especially if you can catch it early,” stresses Wein. “The single most effective thing the patient needs to do is eliminate or at least minimize their carb intake. I have Type 2 Diabetes myself and went nine years living a very healthy life without medicine because I followed a correct diet which did not allow for sugar or carbs.”

A clinical laboratory scientist for more than 20 years and a Physician Assistant for 17 years, Wein started extensive research on Type 2 Diabetes when he himself was diagnosed with the disease.

type-2-diabetes-the-owner-s-manual-daryl-wein

After directing successful treatment for many hundreds of patients by informing them of the correct diet for them, Wein decided to share those secrets with patients and physicians alike in his new book Type 2 Diabetes: The Owner’s Manual (ISBN 978-1522858270, CreateSpace 2016, 159 pages, available on Amazon $11.99 paperback, $6.99 Kindle and Audio Book.

“To my knowledge my book is the only simple owner’s manual for Type 2 Diabetes,” says Wein. “It teaches readers to utilize first the most effective option available to manage their disease and then to fine-tune sugar control with medication when and if needed. The Owner’s Manual is very simple to read and understand.”

While working for Central California Bariatric Surgery Daryl Wein made it his objective to help patients reach their needed weight goal via diet instead of surgery and experienced multiple successes including one patient who lost 149 pounds over 22 months simply by avoiding carbohydrates completely.

Wein stresses that if all people with sugar abnormalities (who are not dependent on insulin) followed the simple advice in Type 2 Diabetes: The Owner’s Manual the impact on their overall health would be immense and the savings for healthcare in the U.S. alone would be in the many billions of dollars.

James A. Surrell, M.D. and author of SOS (Stop Only Sugar) Diet, says: “We have an epidemic of Type 2 diabetes in the USA today, primarily as a result of our dietary habits. Follow the excellent guidelines contained in Type 2 Diabetes: The Owner’s Manual and you will significantly improve your overall health.”

A physician in a review on Amazon using the pen name “Schmutz” writes: “The Owner’s Manual is well written, easy to understand in laymen’s terms and very useful. If diabetics followed Daryl’s recommendations, my job would be much easier and their lives healthier and longer.”

A few of the eye-opening pieces of advice given by Wein in his highly-respected book include:

• There is no need to consume any sugar or starches at all
• Natural fruit and fruit juices are not good for diabetics
• Avoid all forms of alcohol when trying to lose weight
• The only fats known to be harmful are trans-fats which are mainly found in shortening and margarine
• Eating fat does not make you fat and eating fat has never been directly associated with heart disease
• Brown sugar has never been healthier than white sugar, only less pure
• There are almost no carbs in any of the artificial sweeteners so they do not contribute to the elevation of blood sugar.
• Monitoring your sugar 2-3 times a day with a finger stick test is costly and a complete waste of time.

A former flight instructor, Wein also enjoys water skiing, swimming, building houseboats, and playing the bass which he did while earning his living as a musician, playing in clubs for three years. He owns a small plane but his latest flight interest is flying industrial drones legally. Daryl and wife Jann have an adult daughter, an adult son, and three grandchildren.

National Diabetes Month is observed every November so individuals, health care professionals, organizations, and communities across the country can bring attention to diabetes and its impact on millions of Americans. Visit: http://www.diabetes.org.

About Daryl Wein
A native of Niles, Michigan, Wein earned a degree as a Medical Technologist/Clinical Laboratory Scientist from USC Medical Center in 1978 and earned a degree as a Family Practice Physician Assistant from UC Davis School of Medicine in 1999. Since 1999, while working as a PA with Dr. David Olson and Dr. Elaine Madayag in internal medicine, Wein also worked as a PA at Stanislaus County Urgent Care, Oak Valley Hospital ER, Central California Bariatric Surgery, as a contractor for California Correctional Health Care System, and for rural health clinics run by Oak Valley Clinics. He also has done some software development, and is credentialed in California to teach community college classes.

Media Contact: For a review copy of Type 2 Diabetes: The Owner’s Manual or to arrange an interview with Daryl Wein contact Scott Lorenz of Westwind Communications Book Marketing by phone at 734-667-2090 or http://www.book-marketing-expert.com.

New Study Shows Monaghan Medical’s Drug-Free Aerobika® Device Reduces Acute Drug Usage and Costs Following COPD Exacerbations

Real-world study presented at CHEST 2016 Annual Meeting in Los Angeles.

monaghan-medical-corporation-logo

Syracuse, NY, USA — Monaghan Medical Corporation (MMC) today announced that a new study presented to the American College of Chest Physicians (CHEST) shows MMC’s Aerobika® device is effective in reducing drug use for treatment of Chronic Obstructive Pulmonary Disease (COPD).

COPD is a major source of morbidity and mortality in the United States.(i) The Center for Disease Control estimates that COPD medical visits, hospital admissions and lost time costs 36 billion dollars annually.(ii) The recommended course of treatment for acute COPD exacerbations includes antibiotics and oral corticosteroids (OCS).(iii)

The study results revealed today at the CHEST Annual Meeting in Los Angeles, show that those study patients who used the Aerobika® device experienced a significant reduction (57% and 89% reduction, respectively) in the use of antibiotics and OCS in the hospital setting compared to those study patients who did not use the Aerobika® device in addition to the regular COPD medication treatment. These findings are part of a larger 6-month retrospective study that demonstrated a 28% reduction in exacerbations in as little as 30 days of treatment, when used as an add-on to usual COPD medications.

COPD exacerbations can be caused by viral or bacterial infections, in fact pulmonary infections are associated with 50% of COPD hospital admissions(iv) and higher mortality rates.(v) Overproduction of mucous leads to increased rates of infection and inflammation contributing significantly to morbidity and mortality in COPD.(vi)

This study showed for patients in the Aerobika® device cohort, antibiotics were used 57% less and oral corticosteroids were used 89% less than for the cohort without the Aerobika® device within 6 months’ post-exacerbation. The decreased need for short-term drug therapies including antibiotics and OCS, may have reflected better disease control with those patients who used the non-drug device. Additionally, patients in the Aerobika® device cohort exhibited significantly lower costs throughout the study period with an average reduction of $6,347 USD and $9,936 USD per patient at 30 days and 6 months respectively for all in-patient and out-patient hospital costs.

“One of our major goals in developing the Aerobika® device was to safely improve patient outcomes,” said Dominic Coppolo, MBA, RRT, FAARC, Vice President Clinical Strategy and Development at Monaghan Medical. “These real-world findings are encouraging as we continue to conduct additional studies to further demonstrate the impact of our device in this high risk patient population.”

The projected cost of COPD in the U.S. by 2020 has been calculated at $49 billion.(vii) Since COPD exacerbations account for the greatest proportion of burden on healthcare systems,(viii) and readmissions are unwanted and expensive, the simplest way to reduce hospital admissions for COPD is to reduce exacerbations.(ix)

About the Aerobika® device study: A 6-month retrospective cohort study of the US hospital Charge Detail Master (CDM) claims database, conducted between September 2013 and August 2015. This real-word study involved 810 COPD patients with a diagnosis of chronic bronchitis, 405 receiving treatment with the Aerobika® device and 405 propensity score matched controls. The primary outcome was the proportion of patients with moderate-to-severe and severe exacerbations at 30 days. Secondary measures included resource utilization and costs associated with exacerbations.

About The Aerobika® Device
The Aerobika® device is hand-held, easy-to-use, and drug-free. When the patient exhales through the device, intermittent resistance creates positive pressure and oscillations simultaneously, which expands the airways, helps expel the mucus to the upper airways where it can be coughed out and may also aid in improved drug deposition. The Aerobika® device is available in Canada, Mexico, and select European countries including the UK and Germany through Trudell Medical International and in the US via Monaghan Medical Corporation. (http://www.trudellmed.com/products/aerobika)

About Monaghan Medical Corporation (MMC, USA)
MMC offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® aVHC and the Aerobika® device exclusively in the United States. MMC’s strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. MMC focuses on developing cost-efficient, outcome-based solutions for its customers. (http://www.monaghanmed.com)

For clinical inquiries, please contact:
Dominic P. Coppolo, MBA, RRT, FAARC
Vice President of Clinical Strategy and Development
Monaghan Medical Corporation
1-800-343-9071

COPD Facts in USA(x)
– More than 15 million people report being diagnosed with COPD but millions more may not have been diagnosed
– COPD accounts for 10.3 million medical visits and 1.5 million hospital admissions
– 23 percent of hospitalized patients are re-hospitalized within 30 days
– For COPD exacerbations, Medicare healthcare expenditures for re-hospitalization are the third highest
– The total cost of COPD hospitalizations is estimated at $36 billion per year

i Ford ES, et al. Chest 2013;144(1):284-305.
ii Ford ES, et al. Chest. 2015 Jan;147(1):31-45.
iii Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2015.
iv Tesfaigzi Y et al. Clinical and Applied Immunology Reviews 2006;6(1):21-36
v Burgel PR, Martin C. European Respiratory Review 2010;19(116):94-96.
vi Hogg JC et al. The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease The New England Journal of Medicine 2004;350(26):2645-2653
vii Ford ES, et al. Chest. 2015 Jan;147(1):31-45.
viii Khakban A, et al. Am J Respir Crit Care Med. 2016
ix Mittmann et al. Respir Med. 2008 Mar;102(3):413-21.
x Ford ES, et al, Chest. 2015 Jan;147(1):31-45.

Non-Drug Device Reduces COPD Exacerbations

Real-World Study Presented at ERS 2016, London UK.

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Plattsburgh, NY, USA — Monaghan Medical Corporation (MMC) today announced results from a real-world study, evaluating the efficacy of the Aerobika® device in reducing chronic obstructive pulmonary disease (COPD) exacerbations. These results were presented at the European Respiratory Society International Congress in London, and are anticipated to impact the future management of COPD patients with a history of exacerbations.

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Exacerbations are a worsening of symptoms and are the most common reason for COPD hospital admissions (1). During an exacerbation, airways are compromised by inflammation and mucus buildup, causing patients to be poorly responsive to usual COPD treatments (2). Recovery can be delayed for weeks, resulting in further airway deterioration and putting patients at risk of recurrent exacerbations. In fact, approximately 1 in 5 admitted patients required re-hospitalization within 30 days (3).

Clinicians, hospitals, and healthcare systems around the globe are now focusing their attention on this critical post-exacerbation period with the goal of reducing subsequent re-admissions and maintaining the long-term health of their COPD patients.

In the 6-month study, the Aerobika® device demonstrated a clinically-significant reduction in exacerbations in as little as 30 days of treatment, when used as an add-on to usual COPD medications. “These results carry important implications for how we manage COPD patients with a history of exacerbations,” says Brian Carlin, MD, FCCP, FAASM. “Adding the Aerobika® device to our current COPD treatment protocols could significantly improve patient outcomes while decreasing the burden on our healthcare resources.”

The Aerobika® device has been previously validated in clinical studies, demonstrating improvements in airway ventilation, lung function and quality of life. “This new study has validated the use of this device in a real-world setting, providing a drug-free addition to post-exacerbation therapy for COPD patients.” says Dr. Jason Suggett, Group Director of Science & Technology at Trudell Medical International (TMI), the sister company for MMC.

About the Aerobika® device study
The study profiled here is a 6-month retrospective cohort study of the hospital Charge Detail Master (CDM) claims database, conducted between September 2013 and August 2015. This real-word study involved 810 patients, 405 receiving treatment with the Aerobika® device and 405 propensity score matched controls. The primary outcome was the proportion of patients with moderate-to-severe and severe exacerbations at 30 days. Secondary measures included resource utilization and costs associated with exacerbations.

About The Aerobika® Device
The Aerobika® device is hand-held, easy-to-use, and drug-free. When the patient exhales through the device, intermittent resistance creates positive pressure and oscillations simultaneously, which stents open the airways, mobilizes and assists in moving mucus to the upper airways where it can be coughed out. This may also aid in improved drug deposition. The Aerobika® device is available in Canada, Mexico, and select European countries including the UK and Germany through TMI and in the US via Monaghan Medical Corporation. (http://www.monaghanmed.com/Aerobika)

About Monaghan Medical Corporation (MMC, USA)
MMC, an affiliate of TMI, offers leading aerosol drug delivery devices and respiratory management products including AeroEclipse® II BAN, AeroChamber Plus® brand aVHC, and the Aerobika® device exclusively in the United States. Our strength lies in product development around core capabilities in mechanical design complimented by collaboration with a state-of-the-art aerosol research laboratory. We focus on developing cost-efficient, outcome-based solutions for our customers. (http://www.monaghanmed.com)

About Trudell Medical International (TMI)
TMI designs, develops and manufactures a wide range of medical devices and is home to a global aerosol lab and research center. From the flagship AeroChamber® Brand of Valved Holding Chamber (VHC) and the latest award-winning Aerobika® device, to custom designed products and systems, our best-in-class respiratory management products are sold in over 110 countries. Their efficacy has been validated in hundreds of peer-reviewed articles from various medical journals. (http://www.trudellmed.com)

References:
[1] O’Donnell et al. Can Respir J. 2007;14(Suppl B):5B-32B.
[2] O’Donnell DE, Parker CM. Thorax. 2006;61(4):354-61.
[3] Shah et al. CHEST. 2016 May 7 [Epub ahead of print].

For clinical inquiries, please contact:
Jason Suggett, Group Director Science and Technology
Trudell Medical International
519-455-7060 ext. 2270

Monaghan Medical Introduces Manometer Adapter to Measure Treatment with Aerobika® OPEP Device

New Adapter Tracks Airway Pressure Visually, Ensuring Therapeutic Effectiveness of Respiratory Treatment.

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Plattsburgh, NY, USA (January 21, 2016) — Monaghan Medical Corporation (MMC) (http://www.monaghanmed.com), a leader in the development, manufacture, and marketing of respiratory devices, today announced the release of a new Manometer Adapter for its Aerobika® Oscillating Positive Expiratory Pressure (OPEP) device-a drug-free, clinically supported device that reduces coughing and breathlessness, increases lung hygiene, and improves gas transfer. The Manometer Adapter serves as a visual compliance tool for the Aerobika® OPEP to assist respiratory therapists and patients in assessing respiratory therapy that calls for active exhalation.

The MMC Aerobika® OPEP device improves respiration by clearing mucus from the lungs through exhalation. OPEP therapy is highly effective in postoperative patients for airway clearance and lung hygiene, and for patients with chronic respiratory conditions such as cystic fibrosis. With the addition of a Manometer Adapter, respiratory therapists, clinicians, and patients can literally see with their own eyes how well the patient is using the device.

The Aerobika® OPEP device works by using active exhalation: The patient wraps his or her mouth around the OPEP mouthpiece and exhales, while the device uses pulses of air resistance to release mucus trapped in smaller air pathways. The Manometer Adapter allows clinicians to measure the pressure exerted by active exhalation to determine therapeutic effectiveness. It is ideal for clinical training, ensuring that the OPEP device is used properly.

The Manometer Adapter-which has an easy-to-read scale that shows green when active exhalation is in the target zone of 5 cm to 20 cm H2O-provides immediate patient feedback and confirms that the patient is achieving therapeutic pressure every time the OPEP device is used.

“Postoperative patients and patients with severe respiratory conditions needed a new kind of respiratory treatment,” says Dom Coppolo, Vice President of Clinical Strategy and Development at Monaghan Medical Corporation. “That’s why we developed the Aerobika® OPEP Therapy System-to help treat ailments with a productive cough seeking a non-therapeutic method of removing mucus from the lungs. With the addition of the Manometer Adapter, we now have an OPEP device that is easy to use and easy to monitor. The Manometer Adapter provides a baseline for active exhalation therapy so practitioners can measure patients’ recovery progress.

“We are committed to providing products that ensure patients continue treatment and control their symptoms,” Coppolo says. “Providing metrics to measure treatment efficacy only speeds recovery.”

The Aerobika® OPEP is suitable for various patient treatments, such as post-operative thoracic recovery, lung volume expansion therapy, and atelectasis treatment, reducing the risk of pulmonary complications. The Aerobika® OPEP is easy to use, has no side effects or interactions since it is drug-free, and, with the new Manometer Adapter, makes it easier than ever to monitor therapeutic pressure levels.

For more information, visit http://www.Aerobikaopep.com.

About Monaghan Medical
Monaghan Medical Corporation (MMC), headquartered in Plattsburgh, New York (USA), is a leader in the development, manufacture, and marketing of respiratory devices, from the flagship AeroChamber® Brand of Valved Holding Chamber (VHC) for asthma patients to the latest state-of-the-art Aerobika® OPEP therapy. MMC’s products are developed and validated by its sister company’s world-renowned Trudell Medical Aerosol Institute and are supported by more than 500 peer reviewed and published articles.

Contact:
Dominic P. Coppolo
Vice President of Clinical Strategy and Development
Monaghan Medical Corporation
800-343-9071
dcoppolo@monaghanmed.com
http://www.monaghanmed.com

Village Yoga Will Now Offer 4 Classes with a Donation Price Option, Helping Those Living in, or Seeking, Recovery from Alcohol and Drug Addiction

This unique, neighborhood yoga studio, has decided that many who need yoga can’t afford it and are offering 4 scheduled classes by Donation to all who really need it – those suffering from substance abuse & dependancy, with an option to pay later.

Village Yoga

Franklin, MI, USA — This unique, neighborhood yoga studio, has decided that many who need yoga can’t afford it and are offering 4 scheduled classes by Donation to all who really need it – those suffering from substance abuse & dependancy, with an option to pay later.

Village Yoga offers the requisite classes of Ashtanga, Vinyasa and Slow Yoga (Healthy Backs) along with more specialized classes of Yin, Restorative/Yoga Nidra and Satsang – Cosmic Truth Discussion Classes. Private and Group classes are also available in the studio or in other locations.

What makes this studio most unique are the 4 classes that are offered by “donation”, including the packed Recovery Class offered every Saturday night at 6pm. The Owner, Merrily McDonald, is in Recovery and has helped many sufferers from addiction and alcoholism over the years. Merrily has also been awarded a 200 Hour Certification to practice as a Chemical Dependency Counselor in the State of Michigan.

Transformation Station Enjoy a Raw, Organic Juice and/or a Freshly Frozen Fruit Smoothie after a yoga class or while visiting Franklin Village.

Transformation Station
Enjoy a Raw, Organic Juice and/or a Freshly Frozen Fruit Smoothie after a yoga class or while visiting Franklin Village.

To boost a healthy life-style, the studio is the home to Transformation Station, an Organic Raw Juice and Freshly Frozen Fruit Smoothie Bar, open to students and the public. With a varied and healthy menu (if you like, you can make up your own), it’s a wonderful addition that the students enjoy after a class or when driving through the Village.

When asked about the business, Merrily, founder and owner, emphasized the amazing story behind the beginnings of Village Yoga, saying “The studio was a gift – the young couple who had put their love into creating this beautiful space realized that it was too overwhelming. The studio, with everything in it – all of the accessories, stereo, student list – even brand new floors and lighting – was given for nothing. The studio is thriving, filled with laughing, happy students, over 16 months later! Life sure is a journey.”

Village Yoga offers classes 7 days a week with classes every morning (except Monday) & evening. The Donation Classes include Satsang, a Group Study on Mondays at 7:15pm, Recovery Yoga on Saturdays at 6pm, Gentle Slow Yoga (great for beginners) at Noon and a Restorative/Yoga Nidra Class at 5:45pm, both on Sundays. Discussion is available to practice now & pay later. Gift Certificates for yoga and beverages are also available.

The studio and Transformation Station are located in the heart of Historic Franklin Village at 32751 Franklin Road Franklin MI, 48025.

Interested individuals and businesses are invited to visit the mobile-friendly website, Village Yoga, call 248.797.0579 for more information.

Media Contact:
Merrily McDonald
Village Yoga & Transformation Station
32751 Franklin Road
Franklin, MI 48025
248-797-0579
villageyogafranklin@gmail.com
http://www.villageyogafranklin.com

European Pharmaceutical Review Launches Their New Media Planner for 2016

The publication European Pharmaceutical Review today announces the official launch of their new media planner for 2016.

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Brasted, United Kingdom (November 17, 2015) — The publication European Pharmaceutical Review today announces the official launch of their new media planner for 2016.

European Pharmaceutical Review

“Throughout 2015, we have seen a very successful year unfold, with visitor numbers soaring by more than 230% and website registrations up by more than 78%. These figures show that our audience is becoming more relevant and larger in size to fit our clients’ needs” Graeme Cathie, Publisher, European Pharmaceutical Review.

Responses from their 2015 industry survey confirmed that:
• 95% of their community work in pharma, biotech or academia
• More than 91% of their visitors have influential purchasing power
• They have an online satisfaction rating of over 93%
• Over 78% of their print readers are involved in the decision making process

Each of their print issues goes to the top 25 pharmaceutical and top 25 biotechnology companies as well as the leading 25 life science academic institutions. Now that advertising opportunities are nearly sold out for 2015 both digitally and in print, European Pharmaceutical Review is now selling advertising and sponsorship across its portfolio for 2016.

About European Pharmaceutical Review
European Pharmaceutical Review is the leading publication and website for information on technologies in drug discovery and manufacturing. Published bi-monthly, every issue offers a high level of technical and business contributions from the world’s leading pharmaceutical companies and academic institutions, coupled with a variety of exciting new features including interviews, updates and profiles.

http://www.europeanpharmaceuticalreview.com

For further information, please contact:
Graeme Cathie, Publisher
European Pharmaceutical Review
T: +44 (0)1959 563311
E: gcathie@russellpublishing.com
W: http://www.europeanpharmaceuticalreview.com

Drug Target Review Launches Their New Media Planner for 2016

The publication Drug Target Review today announces the official launch of their new media planner for 2016.

Russell Publishing Ltd Logo

Brasted, United Kingdom (November 16, 2015) — The publication Drug Target Review today announces the official launch of their new media planner for 2016.

Drug Target Review

“Throughout 2015, we have seen a very successful year unfold, with visitor numbers soaring by more than 400%. These figures show that our audience is becoming more relevant and larger in size to fit our clients’ needs” Nic Losardo, Publisher, Drug Target Review.

Responses from their 2015 industry survey confirmed that:
– More than 92% of their community work in Pharma, Biotec or Academia
– 75% of their visitors have influential purchasing power
– They have an online satisfaction rating of over 92%
– More than 73% of their print readers audience are involved directly in the purchasing decisions

Each of their print issues are sent to the top 25 pharmaceutical and top 25 biotechnology companies as well as the leading 25 life science academic institutions. Now that advertising opportunities are nearly sold out for 2015 both digitally and in print, Drug Target Review is now selling advertising space and sponsorship across its portfolio for 2016.

About Drug Target Review
Drug Target Review provides a voice for the drug discovery industry, promoting the latest research and developments, funding projects, and cutting-edge technological developments. We support academia, campus companies, tech transfers, research facilities and Pharma by creating a community with the goal of educating and sharing information and news. This community of diverse individuals is able to keep up to speed with research, news and funding as it happens through print, online and workshops.

http://www.drugtargetreview.com

For further information, please contact:
Nic Losardo, Publisher
Drug Target Review
T: +44 (0)1959 563311
E: nlosardo@russellpublishing.com
W: http://www.drugtargetreview.com